Anti-ZNF331 Rabbit Polyclonal Antibody for WB, ELISA - Q9NQX6

Core Product Specifications and Parameters

Biological Background: ZNF331 Function and Localization

• Zinc finger protein 331 (ZNF331), also known as RITA (rearranged in thyroid adenomas), ZNF361, or ZNF463, is a C2H2-type zinc finger transcription factor encoded by the ZNF331 gene in humans.
• ZNF331 may play a role in transcriptional regulation and is implicated in spermatogenesis, as it is specifically expressed in testis tissue.
• The protein contains multiple C2H2 zinc finger domains, which mediate DNA binding and possibly protein-protein interactions, typical of the krueppel C2H2-type zinc-finger family.
• Localizing to the nucleus, ZNF331 functions within the chromatin environment to modulate gene expression.
• UniProt annotations indicate post-translational modifications including ubiquitin conjugation (Ubl conjugation) and isopeptide bond formation, which may regulate its stability or activity.
• Keywords associated with ZNF331 include DNA-binding, metal-binding (zinc), repeat domains, and transcriptional regulation, reflecting its molecular role.

Experimental Guidance and Technical Tips

• This rabbit polyclonal antibody is raised against a recombinant protein encompassing amino acids 50-130 of human ZNF331, and is recommended for Western blot (WB) and ELISA applications.
• With cross-reactivity to human, mouse, and rat, the antibody can be considered for studies in these species; however, validation in the relevant sample system is advised.
• For WB, a band of approximately 54 kDa may be detected. Using testis lysate as a positive control, given the testis-specific expression of ZNF331, is recommended.
• In ELISA, optimal antibody concentration and assay conditions should be determined empirically, as no pre-validated dilutions are provided.
• As polyclonal antibodies may recognize multiple epitopes, confirm specificity by evaluating potential isoforms or using a knockdown/knockout model.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as a comprehensive sourcing partner for IVD raw materials, supporting diagnostic manufacturers, laboratories, and research institutes from concept to clinic. For transcription factors and testis-specific targets such as ZNF331, we offer validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and rare target raw-material procurement. Streamline your assay development with CamelBio’s integrated supply and technical services.