Anti-ZNF324 Polyclonal Antibody for IHC-P, IF/ICC, ELISA - O75467

Core Product Specifications and Parameters

Biological Background: ZNF324 Function and Localization

• Zinc finger protein 324A (ZNF324, also designated ZNF324A or ZF5128) belongs to the Krüppel C2H2‑type zinc‑finger family, characterized by multiple tandem zinc‑finger repeats that confer DNA‑binding capacity.
• The protein likely functions as a transcription factor, with UniProt annotation indicating a role in transcriptional regulation and potential involvement in the control of cell proliferation.
• ZNF324 localizes predominantly to the nucleus, consistent with its predicted role in chromatin interaction and gene expression modulation.
• Tissue profiling shows high expression in immune‑associated organs—spleen, thymus, and peripheral blood mononuclear cells (PBMCs); lower levels in prostate, ovary, small intestine, colon mucosal lining, placenta, lung, and pancreas; and very weak expression in liver and kidney.
• The protein is rich in zinc‑finger motifs and is annotated with the keywords DNA‑binding, metal‑binding, nucleus, transcription, transcription regulation, zinc, and zinc‑finger.
• The ZNF324 gene (GeneID: 25799) encodes a protein with a predicted molecular mass of approximately 61 kDa.

Experimental Guidance and Technical Tips

• The immunogen comprises residues 271–553 of human ZNF324, a segment that spans part of the zinc‑finger domain array; consider its use in applications requiring detection of native epitopes.
• This antibody has been tested in IHC‑P, IF/ICC, and ELISA; for each technique, optimize the dilution and antigen retrieval conditions using appropriate positive tissues such as spleen or thymus.
• Cross‑reactivity with mouse and rat is reported; verify performance in your model system, as sequence conservation in the target region may influence reactivity.
• For western blot, a band at ~61 kDa is expected; ensure efficient protein extraction and include relevant controls from human cell lines or tissues.

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CamelBio streamlines IVD raw‑material sourcing for diagnostic manufacturers and research laboratories. From validated antibody pairs to optimized polyclonal antibodies like ZNF324 Rabbit pAb, we supply bulk ancillary reagents and assist with rare‑target acquisition. Trust CamelBio to bridge your concept‑to‑clinic journey with confidence.