Anti-ZNF273 Rabbit Polyclonal Antibody for WB, ELISA - Q14593

Core Product Specifications and Parameters

Biological Background: ZNF273 Function and Localization

• ZNF273, also known as HZF9, is a zinc finger protein that belongs to the Krüppel-type C2H2 zinc finger family, characterized by multiple tandem zinc finger motifs that mediate DNA binding.
• It is predicted to function as a transcription factor, potentially regulating gene expression through direct interaction with DNA.
• The protein is localized to the nucleus, consistent with its role in transcriptional regulation.
• ZNF273 undergoes alternative splicing, generating multiple transcript variants that may encode distinct protein isoforms.
• Keywords associated with ZNF273 include DNA-binding, metal-binding (zinc), transcription, transcription regulation, and repeat region, reflecting its structural and functional characteristics.
• The predicted molecular weight is approximately 65 kDa (UniProt: 64971 Da), aligning with its observed size in Western blot applications.

Experimental Guidance and Technical Tips

• The immunogen corresponds to a specific region (aa 210-260) of human ZNF273, which may contribute to target specificity; consider validating in relevant cell or tissue lysates.
• For Western blot, a band around 65 kDa is expected; however, alternative splicing may produce isoforms of different sizes, so confirm band patterns with appropriate controls.
• For ELISA, consider using the antibody as a capture or detection reagent after confirming its performance in your specific assay system.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research laboratories with reliable access to high-quality IVD raw materials, including validated antibodies for transcription factor targets like ZNF273. Our portfolio covers optimized polyclonal and monoclonal antibodies, recombinant proteins, and ancillary reagents to support your assay development from concept to clinic. For rare or custom targets, our sourcing expertise ensures a streamlined supply chain, enabling accelerated diagnostic innovation.