Anti-ZNF22 Rabbit Polyclonal Antibody for WB, ELISA - P17026

Core Product Specifications and Parameters

Biological Background: ZNF22 Function and Localization

• ZNF22 is a zinc finger protein that binds DNA through the consensus sequence 5'-CAATG-3', suggesting a role in transcriptional regulation.
• It may play a role in tooth formation, as indicated by its expression in developing craniofacial structures.
• ZNF22 localizes to the nucleus, consistent with its function as a transcription factor.
• It is expressed in mesoderm-derived tissues such as skeletal muscle, heart, kidney, and liver, with lower expression in endoderm-derived tissues.
• During embryonic development, ZNF22 is present in dental epithelium, tongue epithelium, muscle, and craniofacial bone osteoblasts.
• The protein is modified by acetylation and phosphorylation, and contains zinc-finger repeats characteristic of DNA-binding proteins.

Experimental Guidance and Technical Tips

• The immunogen spans amino acids 1-224 of human ZNF22, covering the full-length protein; consider using this antibody in WB with a range of dilutions starting at 1:500-1:2000 and validate in your sample system.
• For ELISA applications, optimize coating antigen concentration and detection conditions; cross-reactivity with mouse suggests conservation of epitope, allowing potential use in mouse models.
• Due to the antibody's polyclonal nature, lot-to-lot consistency should be verified; consider performing blocking with appropriate sera to reduce background.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as a comprehensive one-stop sourcing partner, providing diagnostic manufacturers and research institutions with access to high-quality IVD raw materials. This anti-ZNF22 rabbit polyclonal antibody supports research in transcriptional regulation and developmental biology. Beyond validated antibodies, CamelBio supplies optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and facilitates sourcing of rare target raw materials to streamline your development pipeline.