Anti-ZNF20 Rabbit PolymAb® for WB, IF-P, IHC-P, ELISA - P17024

Core Product Specifications and Parameters

Biological Background: Zinc finger protein 20 Function and Localization

• Zinc finger protein 20 (ZNF20), also known as KOX13, is a member of the Krüppel-type zinc finger protein family, characterized by multiple C2H2-type zinc finger repeats that facilitate DNA binding.
• It is predicted to function as a transcription factor, potentially regulating gene expression through sequence-specific DNA interaction.
• ZNF20 localizes to the nucleus, consistent with its role in transcriptional control.
• The protein contains several zinc finger motifs, which coordinate zinc ions and are essential for its structural integrity and DNA-binding activity.
• No post-translational modifications have been reported for ZNF20, though further experimental validation is required.
• Keywords from UniProt highlight its involvement in transcription regulation and its metal-binding properties.

Experimental Guidance and Technical Tips

• The immunogen comprises amino acids 51–118 of human ZNF20; researchers may anticipate reactivity towards this region and consider using full-length protein controls for validation.
• For Western blotting (WB), a band around 62 kDa is expected; sample preparation and loading amounts should be optimized for the endogenous expression level in the target cell or tissue.
• In immunofluorescence (IF) and immunohistochemistry (IHC), nuclear staining is anticipated; appropriate fixation and permeabilization protocols should be tested.
• This antibody has reported cross-reactivity with mouse and rat; when using these species, validate the antibody in the relevant sample system, as sequence homology may affect performance.
• For ELISA applications, the recombinant protein used as immunogen may serve as a positive control; consider pairing with a suitable detection antibody.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers a comprehensive portfolio of IVD raw materials, including this ZNF20 rabbit polynomab, to support your transcriptional regulation studies. Whether you need validated antibody pairs, bulk ancillary reagents, or sourcing assistance for rare targets, our team is ready to assist. Partner with CamelBio for streamlined procurement from discovery to diagnostic development.