Anti-ZNF16 (HZF1/KOX9) Polyclonal Antibody for WB and ELISA - P17020

Core Product Specifications and Parameters

Biological Background: ZNF16 Function and Localization

• ZNF16, also known as HZF1 or KOX9, is a zinc finger protein that functions as a transcriptional activator.
• It promotes cell proliferation by facilitating the S to G2/M phase transition in the cell cycle.
• ZNF16 is involved in erythroid and megakaryocytic differentiation induced by hemin and PMA, respectively.
• It also acts as an inhibitor of apoptosis.
• The protein localizes to the nucleus.
• ZNF16 is ubiquitously expressed.
• Key characteristics include DNA-binding zinc finger repeats, acetylation, isopeptide bond modifications, and a role as a mitogen.
• The molecular weight is approximately 76 kDa, consistent with the product specification.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal region (aa 1-210), which may be suitable for detecting endogenous ZNF16.
• For WB, consider validating the antibody in nuclear extracts given the protein’s nuclear localization.
• For ELISA, perform appropriate titration and include relevant negative and positive controls.
• Confirm specificity by testing in ZNF16-overexpressing or knockdown cell models.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research institutes with comprehensive IVD raw-material solutions. For ZNF16-related studies in transcription, cell cycle, and apoptosis, we offer validated antibody pairs, optimized polyclonal antibodies like this anti-ZNF16 pAb, and bulk ancillary reagents. Our rare-target sourcing capabilities ensure seamless supply for your diagnostic pipeline.