Anti-ZNF134 Rabbit Polyclonal Antibody for WB and ELISA - P52741

Core Product Specifications and Parameters

Biological Background: ZNF134 Function and Localization

• Zinc finger protein 134 (ZNF134) belongs to the C2H2-type zinc finger family and contains multiple zinc finger domains predicted to mediate DNA binding.
• ZNF134 likely functions as a transcriptional regulator, participating in the control of gene expression, though its precise molecular targets remain to be fully characterized.
• The protein localizes to the nucleus, consistent with a role in transcriptional regulation.
• Alternative splicing of the ZNF134 gene generates multiple transcript variants, which may produce protein isoforms with potentially different regulatory properties.
• ZNF134 can undergo post-translational modifications, including ubiquitination (isopeptide bond formation) and potentially other ubiquitin-like conjugations, which may regulate its stability or activity.
• It has been identified in proteomics screens, supporting its expression in human cells and tissues.

Experimental Guidance and Technical Tips

• The immunogen spans amino acids 73–170, a central region of ZNF134; consider that the antibody may detect full-length protein and possibly some isoforms sharing this sequence.
• For Western blotting, expect a band near 48 kDa; validate reactivity using positive and negative cell lines or recombinant protein controls.
• In ELISA applications, perform a dilution series to determine the optimal antibody working concentration for your specific assay format.
• As ZNF134 is a transcription factor, its endogenous expression might be low in certain cell types; nuclear enrichment may enhance signal detection.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers a comprehensive portfolio of IVD raw materials, including validated antibody pairs and polyclonal antibodies for transcription factor and zinc finger protein research. This anti-ZNF134 polyclonal antibody can be incorporated into diagnostic or research workflows, with support for bulk ancillary reagents and sourcing of rare targets. Our end-to-end services span from concept to clinic, ensuring reliable material continuity for your assay development needs.