Anti-WFDC1 Rabbit Polyclonal Antibody for WB, IF/ICC, ELISA - Q9HC57

Core Product Specifications and Parameters

Biological Background: WFDC1 Function and Localization

• WFDC1 (WAP four-disulfide core domain protein 1), also known as prostate stromal protein ps20, is a secreted protein belonging to the WFDC (Whey Acidic Protein four-disulfide core) family.
• It functions as a growth inhibitor, playing a role in the regulation of cell proliferation.
• The protein contains a WAP domain with four disulfide bonds, characteristic of serine protease inhibitors, suggesting a role in extracellular matrix remodeling or protease regulation.
• WFDC1 is classified as a secreted serine protease inhibitor, consistent with its signal peptide and extracellular localization.
• Its keywords include "Disulfide bond," "Protease inhibitor," "Serine protease inhibitor," and "Secreted," underlining its structural and functional properties.

Experimental Guidance and Technical Tips

• The immunogen corresponds to a partial sequence (amino acids 111-220) of human WFDC1, which may improve specificity for the target protein.
• For Western blot, a band around 24 kDa may be expected based on the predicted molecular weight.
• When performing immunofluorescence or ICC, ensure appropriate permeabilization and controls given the secreted nature of WFDC1.
• Validate the antibody in the relevant sample system (e.g., human or mouse tissues) to confirm reactivity.
• Use appropriate blocking agents to reduce non-specific binding in ELISA.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers, labs, and research institutes a streamlined sourcing solution for IVD raw materials, from antibodies to ancillary reagents. As part of our extensive portfolio, this WFDC1 antibody supports research into growth inhibition and protease-related pathways. Whether you need validated antibody pairs, bulk monoclonal/polyclonal antibodies, or rare target sourcing, CamelBio bridges your concept-to-clinic journey.