Anti-USP24 Rabbit Monoclonal Antibody for WB, ELISA - Q9UPU5

Core Product Specifications and Parameters

Biological Background: USP24 Function and Localization

• USP24 (Ubiquitin carboxyl-terminal hydrolase 24) is also designated ubiquitin-specific-processing protease 24 and deubiquitinating enzyme 24.
• It acts as a ubiquitin-specific protease that modulates cell survival by regulating the protein stability of substrates such as DDB2, MCL1, and TP53.
• USP24 plays a positive role in ferritinophagy, the lysosomal degradation of ferritin that releases free iron.
• As a member of the hydrolase and thiol protease families, USP24 contributes to the ubiquitin conjugation pathway and has been implicated in host-virus interactions.
• USP24 is identified as a phosphoprotein in proteomics studies, suggesting regulation by phosphorylation.

Experimental Guidance and Technical Tips

• The immunogen corresponds to a region within amino acids 2500–2600; consider verifying the epitope accessibility in your target samples.
• For Western blot (WB), expect a band near 294 kDa; optimizing gel percentage and transfer conditions for high-molecular-weight proteins is advisable.
• In ELISA applications, the synthetic peptide immunogen may serve as a positive control to assess antibody binding.
• Validate detection of endogenous USP24 in relevant human, mouse, or rat cell lines known to express the target.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is a dedicated one-stop partner for IVD raw materials, offering diagnostic manufacturers, laboratories, and research institutes access to validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare target sourcing. For USP24, a key deubiquitinase implicated in cell survival, ferritinophagy, and the ubiquitin-proteasome pathway, CamelBio provides reliable raw materials—like this USP24 Rabbit mAb—to support your assay development and translational research needs.