Anti-TXNL4B Polyclonal Antibody for WB, IF/ICC, ELISA - Q9NX01

Core Product Specifications and Parameters

Biological Background: TXNL4B Function and Localization

• TXNL4B (Thioredoxin-like protein 4B), also known as Dim1-like protein (DLP) or Dim2, is a 149-amino acid protein encoded by the TXNL4B gene.
• It plays an essential role in pre-mRNA splicing, functioning as a component of the spliceosome.
• TXNL4B is required for cell cycle progression, specifically at the S/G2 transition, linking splicing activity to cell cycle control.
• The protein localizes to the nucleus, consistent with its involvement in mRNA processing.
• According to UniProt keywords, TXNL4B is associated with mRNA splicing, cell cycle, and nucleus, and has a reference proteome status.

Experimental Guidance and Technical Tips

• The immunogen is a recombinant fusion protein covering the full-length TXNL4B (aa 1-149), suggesting the antibody should recognize the native protein. For western blot (WB), the predicted molecular weight is approximately 17 kDa.
• For immunofluorescence (IF/ICC), a nuclear staining pattern is expected. Consider co-staining with a nuclear marker to confirm localization.
• This antibody is also validated for ELISA. For quantitative assays, pairing with a detection antibody may be needed. Optimize coating antigen and antibody concentrations empirically.
• As reactivity is reported for human and mouse, validate the antibody in the relevant species' sample system (e.g., cell lines, tissue lysates) before use.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio streamlines IVD raw material procurement, offering a comprehensive portfolio of validated antibodies, including monoclonal and polyclonal formats, antibody pairs, and ancillary reagents for the diagnostics industry. For targets like TXNL4B, which are involved in mRNA splicing and cell cycle regulation, CamelBio can provide bulk quantities, custom production, and rare target sourcing to support your assay development from concept to clinic. Our B2B approach ensures reliable supply chains and technical consultation to accelerate your diagnostic workflows.