Anti-TXLNA Rabbit Polyclonal Antibody for WB, ELISA - P40222

Core Product Specifications and Parameters

Biological Background: Alpha-taxilin Function and Localization

• Alpha-taxilin (TXLNA) is encoded by the TXLNA gene, also known as IL14 or TXLN, and belongs to the taxilin family of coiled-coil proteins.
• The protein is thought to play a role in intracellular vesicle trafficking, potentially regulating calcium-dependent exocytosis in neuroendocrine cells.
• Tissue expression is ubiquitous, with significantly higher levels observed in heart, kidney, liver, and pancreas.
• Structural features include coiled-coil domains and phosphorylation sites, suggesting regulation by post-translational modification.
• Keywords associated with P40222 include coiled coil, exocytosis, phosphoprotein, and reference proteome, reflecting its functional classification.

Experimental Guidance and Technical Tips

• The immunogen was raised against recombinant protein corresponding to amino acids 1–160 of human TXLNA. This N-terminal region may be suitable for detecting both full-length and potential isoforms.
• For Western blotting, a band at approximately 62 kDa is expected in human samples. Consider using lysates from tissues with high alpha-taxilin expression (heart, kidney, liver, or pancreas) as positive controls.
• ELISA applications can be developed using recombinant TXLNA protein as a standard; perform titration experiments to optimize coating and detection conditions.
• Since the antibody is polyclonal and recognizes human TXLNA, cross-reactivity with other species is not characterized and should be validated if needed.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio connects diagnostic manufacturers and research laboratories with high-quality IVD raw materials, offering one-stop access to validated antibodies, bulk reagents, and technical support. This anti-TXLNA polyclonal antibody supports studies of vesicle trafficking and exocytosis, and we can assist with sourcing complementary reagents such as antigen standards, matched antibody pairs, or custom production to streamline your development pipeline.