Anti-TUBGCP6 Polyclonal Antibody for WB, IHC-P, ELISA - Q96RT7

Core Product Specifications and Parameters

Biological Background: TUBGCP6 Function and Localization

• TUBGCP6, also known as GCP6, is a component of the gamma-tubulin ring complex (gTuRC).
• The gTuRC mediates microtubule nucleation by regulating the minus-end assembly of alpha-beta tubulin heterodimers, a critical process for microtubule formation. Related references: PMID:11694571 PMID:38305685 PMID:38609661
• TUBGCP6 is essential for centrosome duplication and mitotic spindle formation, ensuring proper chromosome segregation. Related references: PMID:38305685 PMID:38609661 PMID:39321809
• The protein localizes to the cytoplasm and the centrosome, the major microtubule-organizing center.
• TUBGCP6 has a predicted molecular weight of approximately 200 kDa and contains repeat regions; it is subject to alternative splicing.

Experimental Guidance and Technical Tips

• The immunogen consists of a recombinant fusion protein spanning amino acids 600-900 of human TUBGCP6; consider this region when evaluating isoform cross-reactivity.
• For Western blot, expect a band near 200 kDa; use appropriate molecular weight markers and validate with positive and negative controls.
• Cross-reactivity with mouse and rat TUBGCP6 is reported, but sequence alignment is recommended to confirm epitope conservation in these species.
• This antibody is suitable for WB, IHC-P, and ELISA. Optimize antibody dilution and incubation conditions for each application and sample type.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides a one-stop procurement solution for IVD raw materials, from validated antibody pairs to optimized monoclonal and polyclonal antibodies and bulk ancillary reagents, supported by technical and regulatory consulting. For research and diagnostic development focused on gamma-tubulin complex components and microtubule nucleation, CamelBio ensures reliable sourcing of TUBGCP6 antibodies and related products, streamlining your path from concept to clinic.