Anti-TUBGCP5 Polyclonal Antibody for WB, ELISA - Q96RT8

Core Product Specifications and Parameters

Biological Background: TUBGCP5 Function and Localization

• TUBGCP5 (also known as GCP5) is a component of the gamma-tubulin ring complex (gTuRC), with a molecular weight of approximately 118 kDa. Alternative splicing produces multiple isoforms.
• Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation, a critical step in centrosome duplication and spindle formation. Related references: PMID:38305685, PMID:38609661, PMID:39321809
• Belongs to the TUBGCP family; the gene is also designated KIAA1899 and is located on human chromosome 15.
• Localizes to the cytoplasm, cytoskeleton, and specifically to the centrosome at the microtubule organizing center.
• Widely expressed across tissues, with highest levels in heart and skeletal muscle, and moderate expression in brain.
• Associated with keywords such as 3D-structure, Alternative splicing, Cytoplasm, Cytoskeleton, Microtubule, and Reference proteome.

Experimental Guidance and Technical Tips

• The immunogen is a synthetic peptide corresponding to amino acids 100–200 of human TUBGCP5. This region may allow detection of TUBGCP5 in human and rat samples via WB and ELISA.
• Consider optimizing antibody dilution and blocking conditions for your specific assay system.
• As cross-reactivity with rat is indicated, testing with samples from other species may require further validation.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is a dedicated one-stop sourcing partner providing IVD raw materials, technical services, and consulting to diagnostic manufacturers and research laboratories worldwide. This anti-TUBGCP5 polyclonal antibody supports investigations into microtubule nucleation and centrosome biology, with relevance to cell cycle and cancer research. We offer validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and rare target raw-material sourcing to streamline your assay development from concept to clinic.