Anti-TRAPPC2 Monoclonal Antibody for WB, IHC-P, ELISA - P0DI81

Core Product Specifications and Parameters

Biological Background: TRAPPC2 Function and Localization

• TRAPPC2, also known as Sedlin, is a subunit of the trafficking protein particle (TRAPP) complex implicated in vesicular transport from the endoplasmic reticulum to the Golgi apparatus.
• This protein may also play a role in preventing transcriptional repression and cell death induction by ENO1 (by similarity).
• TRAPPC2 localizes to the cytoplasm, perinuclear region, endoplasmic reticulum-Golgi intermediate compartment, and nucleus.
• It is widely expressed in tissues including brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, fetal cartilage, fibroblasts, and lymphocytes.
• Post-translational modifications include phosphorylation, and the gene is subject to alternative splicing.
• Mutations in TRAPPC2 are associated with disease; it is annotated as a disease variant in databases.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N‑terminal region (aa 1–100), which may detect all isoforms if this region is conserved; verify in relevant sample systems.
• For western blot, consider using whole‑cell lysates from tissues or cell lines known to express TRAPPC2 (e.g., brain, heart, or placenta).
• In immunohistochemistry (IHC‑P), antigen retrieval conditions and antibody concentration should be optimized for the specific tissue type.
• Although validated for ELISA, confirm binding under the specific assay format (direct/indirect/sandwich) using the appropriate recombinant protein or peptide controls.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, laboratories, and research institutes with one-stop access to IVD raw materials and technical support from concept to clinic. This anti-TRAPPC2 monoclonal antibody is backed by our expertise in validated antibody pairs, optimized monoclonal/polyclonal preparations, and bulk ancillary reagents—enabling reliable procurement for vesicular trafficking studies and transcription-related diagnostics. For rare target sourcing or custom development needs, we offer a dedicated supply chain to bridge gaps in your assay development.