Anti-TPPP3 Rabbit Polyclonal Antibody for WB and ELISA - Q9BW30

Core Product Specifications and Parameters

Biological Background: TPPP3 Function and Localization

• TPPP3 (Tubulin polymerization-promoting protein family member 3), also known as TPPP/p20, p20, CGI-38, and p25gamma, is a member of the tubulin polymerization-promoting protein family.
• It functions as a regulator of microtubule dynamics and possesses microtubule bundling activity. Related references: PMID:17105200, PMID:19633818
• TPPP3 is required for embryo implantation and decidualization, possibly by regulating beta-catenin. Related references: PMID:30667362
• Localizes to the cytoplasm and associates with the cytoskeleton.
• Expressed in endometrium during the mid-secretory phase (at protein level).
• Contains acetylation modification and is classified under microtubule-associated proteins.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the full-length protein (aa 1-176), which may recognize multiple isoforms; consider verifying specificity in your model system.
• For WB, a band at ~19 kDa is expected; use appropriate positive controls such as endometrial tissue lysates from human or mouse.
• ELISA suitability has been documented; consider optimizing coating conditions and antibody dilution for your assay format.
• Cross-reactivity with mouse and rat is reported; validation in the specific experimental context is advised.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, laboratories, and research institutes with one-stop access to IVD raw materials, technical services, and consulting—supporting projects from concept to clinic. This anti-TPPP3 antibody is suited for research into microtubule biology, embryo implantation, and endometrial function. Our extensive portfolio includes validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare-target raw-material sourcing to meet your assay development needs.