Anti-TOMM40L Rabbit Polyclonal Antibody for WB, ELISA - Q969M1

Core Product Specifications and Parameters

Biological Background: TOMM40L Function and Localization

• TOMM40L (also known as TOMM40B or protein TOMM40-like) is a potential channel-forming protein that participates in the import of protein precursors into mitochondria.
• The protein localizes to the mitochondrial outer membrane, where it may function as a subunit of the translocase of the outer membrane (TOM) complex.
• TOMM40L is a member of the porin family and is classified as a transmembrane beta strand protein, consistent with its channel-forming role.
• The gene undergoes alternative splicing, generating multiple isoforms that may contribute to functional diversity.
• UniProt keywords associate TOMM40L with ion transport, protein transport, and mitochondrial outer membrane processes.
• Proteomics identification supports its expression and detection in human samples, though tissue-specific distribution is not fully characterized.

Experimental Guidance and Technical Tips

• The immunogen used is a synthetic peptide corresponding to the N-terminal region (amino acids 1-100) of human TOMM40L, suggesting the antibody may detect epitopes in this region.
• This antibody is suitable for Western blot (WB) and ELISA applications; consider optimizing dilutions for your specific experimental system.
• Cross-reactivity with mouse makes it a candidate for rodent model studies; validation in the relevant sample type is advised.
• Given TOMM40L's mitochondrial localization, consider enriching mitochondrial fractions or using appropriate lysis buffers to improve detection sensitivity.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, laboratories, and research institutes with one-stop access to IVD raw materials, technical services, and consulting—covering every stage from concept to clinic. This TOMM40L antibody is part of our broad portfolio for mitochondrial research, supporting studies on protein import mechanisms. We offer validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and rare-target raw-material sourcing to accelerate your assay development.