Anti-TOM1L2 Polyclonal Antibody for WB, ELISA - Q6ZVM7

Core Product Specifications and Parameters

Biological Background: TOM1L2 Function and Localization

• TOM1L2 acts as an adapter protein for myosin VI (MYO6), targeting it to endocytic structures.
  Related references: PMID:23023224
• It recruits clathrin to endosomes, facilitating endocytic trafficking.
  Related references: PMID:16412388
• May regulate growth factor-induced mitogenic signaling.
  Related references: PMID:16479011
• Ubiquitously expressed with higher expression in heart and skeletal muscle.
• Keywords: Alternative splicing, Phosphoprotein, Protein transport, Proteomics identification, Reference proteome, Transport.

Experimental Guidance and Technical Tips

• The immunogen targets amino acids 310-450, a C-terminal region; verify antibody specificity in your model system, as this region may be conserved across species.
• For Western blot (WB), use a standard protocol with appropriate secondary antibodies and detection reagents. Optimize blocking and antibody dilutions for your sample type.
• For ELISA, consider direct or indirect coating methods and validate with recombinant antigen or cell lysates.
• Cross-reactivity with mouse and rat has been reported; confirm reactivity in your specific tissue or cell line.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers comprehensive access to IVD raw materials, supporting diagnostic manufacturers and researchers from concept to clinic. For targets like TOM1L2 involved in endocytic trafficking and signaling, we supply validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare target sourcing. Partner with CamelBio to streamline your assay development and procurement needs.