Anti-TMEM61 Rabbit Polyclonal Antibody for WB and ELISA - Q8N0U2

Core Product Specifications and Parameters

Biological Background: TMEM61 Function and Localization

• TMEM61 is a transmembrane protein predicted to contain multiple transmembrane helices.
• It is localized to the membrane, as indicated by its subcellular annotation.
• The full-length human TMEM61 protein has a calculated molecular weight of approximately 22 kDa, consistent with the detected band in Western blot.
• Encoded by the TMEM61 gene (GeneID: 199964) in humans, this protein is part of the reference proteome and has been identified in mass spectrometry-based proteomics studies.
• The UniProt entry for TMEM61 (Q8N0U2) is a reviewed Swiss-Prot record, confirming its existence and annotation as a membrane protein.

Experimental Guidance and Technical Tips

• The immunogen used is a recombinant fusion protein covering amino acids 91–210 of human TMEM61. Depending on the predicted topology, this region may be intracellular or extracellular; consider this when designing epitope-specific assays.
• For Western blot, expect a band at approximately 22 kDa. Validate specificity in the relevant cell or tissue lysates, ideally with a positive control or knockdown/knockout sample.
• In ELISA applications, optimize coating antigen concentration and antibody dilution to achieve optimal signal-to-noise ratios. Cross-reactivity with other species has not been reported; if working with non-human samples, verify reactivity experimentally.
• Since TMEM61 is a membrane protein, ensure proper solubilization and denaturation conditions during sample preparation to avoid aggregation.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as a comprehensive sourcing partner for IVD raw materials, offering antibodies like this anti-TMEM61 polyclonal antibody to support membrane protein research and assay development. We provide access to validated antibody pairs, optimized monoclonal and polyclonal antibodies, and bulk ancillary reagents, streamlining your path from concept to clinic. Let CamelBio help you secure the right raw materials for your diagnostic needs.