Anti-TMEM192 Monoclonal Antibody for WB, ELISA - Q8IY95

Core Product Specifications and Parameters

Biological Background: TMEM192 Function and Localization

• TMEM192 (Transmembrane protein 192) is a multi-pass transmembrane protein that primarily localizes to the lysosome membrane and late endosome.
• It is strongly expressed in kidney, liver, lung, and pancreas, as indicated by tissue specificity data.
• The protein undergoes alternative splicing, producing multiple isoforms.
• TMEM192 is a phosphoprotein, suggesting regulation by phosphorylation.
• Its structure includes several transmembrane helices, consistent with its membrane localization.
• The molecular weight of the canonical isoform is approximately 31 kDa.

Experimental Guidance and Technical Tips

• The immunogen used corresponds to the full-length human TMEM192 protein, which may support detection of the endogenous protein in relevant samples.
• For Western blot, consider using lysates from tissues with high expression (e.g., kidney, liver, lung, or pancreas) as positive controls.
• Optimize antibody concentration and blocking conditions empirically for each assay.
• In ELISA, verify binding specificity using recombinant TMEM192 protein or peptide fragments.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research laboratories with comprehensive access to IVD raw materials, including validated rabbit monoclonal antibodies like this anti-TMEM192 clone. Our portfolio covers targets involved in lysosomal and endosomal biology, supported by bulk ancillary reagents and rare target sourcing capabilities—helping you bridge from concept to clinic efficiently.