Anti-TIMM29 Rabbit Polyclonal Antibody for WB and ELISA - Q9BSF4

Core Product Specifications and Parameters

Biological Background: TIMM29 Function and Localization

• TIMM29 (also known as TIM29 or C19orf52) is a mitochondrial inner membrane protein and a component of the TIM22 complex.
• The TIM22 complex is a twin-pore translocase that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane, using the membrane potential as the driving force.
• TIMM29 is essential for the stability of the TIM22 complex and is required for the assembly of the TIMM22 protein into the complex.
• It may facilitate cooperation between the TIM22 and TOM complexes by interacting with TOMM40.
• Subcellular localization: Mitochondrion inner membrane.
• The protein is characterized by the presence of a transit peptide and transmembrane helix, and is involved in protein transport and translocation.
• Keywords: 3D-structure, Membrane, Mitochondrion, Mitochondrion inner membrane, Protein transport, Proteomics identification, Reference proteome, Transit peptide, Translocation, Transmembrane, Transmembrane helix, Transport.

Experimental Guidance and Technical Tips

• This antibody is raised against a recombinant protein corresponding to amino acids 78-260 of human TIMM29. For Western blot, consider testing at dilutions optimized for your sample preparation. The predicted molecular weight is approximately 29 kDa; validate with appropriate size markers and controls.
• The antibody has been reported to work in ELISA. When setting up an ELISA assay, consider using the immunogen region as a reference for coating or competition experiments.
• Cross-reactivity has been demonstrated with human and mouse TIMM29. For studies in other species, verify sequence homology before use.
• Given the mitochondrial localization and role in protein import, this antibody may be suitable for investigating TIM22 complex dynamics or mitochondrial biogenesis; appropriate fractionation or immunofluorescence may be required.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your dedicated partner for IVD raw material sourcing, providing a one-stop solution from concept to clinic. This anti-TIMM29 polyclonal antibody supports mitochondrial research and assay development, and we offer a full range of companion reagents including validated antibody pairs, optimized monoclonal and polyclonal antibodies, and bulk ancillary materials. Let CamelBio streamline your supply chain for reliable, high-quality raw materials tailored to your diagnostic needs.