Anti-THAP3 Rabbit Polyclonal Antibody for WB, ELISA - Q8WTV1

Core Product Specifications and Parameters

Biological Background: THAP3 Function and Localization

• THAP domain-containing protein 3 (THAP3) is a member of the THAP protein family characterized by an N-terminal zinc-finger motif that facilitates DNA-binding.
• It is a component of the THAP1/THAP3-HCFC1-OGT transcriptional regulatory complex, which modulates the expression of the RRM1 gene.
• The protein undergoes alternative splicing, producing multiple isoforms with potentially distinct functions.
• THAP3 is classified as a phosphoprotein, implying regulation via phosphorylation events.
• The protein contains a metal-binding domain and is annotated as a zinc-binding protein, consistent with its zinc-finger structure.
• Tissue expression analysis reveals high abundance in heart, skeletal muscle, and placenta, with lower levels in brain, kidney, and liver.
• The predicted molecular mass of THAP3 is approximately 27 kDa.

Experimental Guidance and Technical Tips

• The rabbit polyclonal antibody was raised against full-length human THAP3 recombinant protein (aa 1-239); it may detect multiple isoforms due to alternative splicing. For Western blot, consider validating the expected band size near 27 kDa in your sample lysates.
• In ELISA applications, the antibody can be used as a capture or detection reagent; optimization of coating and blocking conditions is advised for each assay format.
• The antibody is reported to cross-react with mouse and rat THAP3; however, we recommend confirming species-specific reactivity in the relevant sample system before routine use.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as a strategic sourcing partner for IVD manufacturers, offering validated antibodies, bulk ancillary reagents, and rare target raw materials to support your diagnostic development pipelines. This anti-THAP3 polyclonal antibody, suitable for WB and ELISA, is part of our catalog of transcriptional regulation research tools. Contact us to explore custom sourcing, antibody pair optimization, and technical consultation tailored to your project needs.