Anti-TEX101 Polyclonal Antibody for WB, IHC-P, ELISA - Q9BY14

Core Product Specifications and Parameters

Biological Background: TEX101 Function and Localization

• Encoded by the TEX101 gene (also designated SGRG), the protein is alternatively known as cell surface receptor NYD-SP8, scleroderma-associated autoantigen, and spermatogenesis-related gene protein.
• Functions in fertilization by controlling sperm binding to the zona pellucida and migration into the oviduct (By similarity).
• May participate in signal transduction and promote protein tyrosine phosphorylation (By similarity).
• Predominantly expressed in testis and spermatogonia; also detected in blood leukocytes, but not in spermatocytes.
• Localizes to the cell membrane and membrane rafts; additionally present in cytoplasmic vesicles, secretory vesicles, the acrosome, and can be secreted.
• Post-translationally modified as a glycoprotein with a GPI anchor; alternative splicing generates multiple isoforms.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal region (aa 44-150), which may be extracellular or intracellular; verify antigen retrieval conditions for IHC-P.
• For WB in testis lysates, consider reducing and non-reducing conditions due to potential GPI-anchored forms.
• Cross-reactivity with mouse and rat is reported; validate in appropriate tissue samples and consider species-specific protocols.
• As a polyclonal antibody, lot-to-lot consistency should be monitored for critical assays.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as a comprehensive one-stop sourcing bridge for IVD raw materials, supporting diagnostic developers with validated antibody pairs, optimized polyclonal and monoclonal antibodies, and bulk ancillary reagents. For reproductive biology targets such as TEX101, CamelBio enables efficient access to rare-target raw materials and expert technical consultation, streamlining your transition from concept to clinic.