Anti-TCF19 Rabbit Polyclonal Antibody for WB, ELISA - Q9Y242

Core Product Specifications and Parameters

Biological Background: TCF19 Function and Localization

• TCF19 (Transcription factor 19), also known as SC1, is a predicted transcription factor implicated in the regulation of cell cycle progression, particularly at the G1/S transition. Related references: PMID:1868030 PMID:31141247
• TCF19 may exert its regulatory function by binding to promoter elements of target genes, including the FOXO1 transcription factor, influencing their expression. Related references: PMID:31141247
• The protein localizes predominantly to the nucleus, consistent with its role as a transcription factor.
• TCF19 contains zinc-finger motifs and is classified as a metal-binding and phosphoprotein, features typical of many transcriptional regulators.

Experimental Guidance and Technical Tips

• The immunogen is a recombinant fragment spanning the N-terminal region (aa 1-290) of human TCF19, which is likely to generate antibodies recognizing multiple epitopes, suitable for both WB and ELISA.
• Given its polyclonal nature, it is advisable to confirm lot-to-lot consistency and titrate the antibody for optimal performance in your specific assay conditions.
• Cross-reactivity with mouse and rat is reported; for these species, validate the antibody with appropriate positive and negative controls to ensure specificity.
• Consider using this antibody as a tool to investigate TCF19’s role in cell cycle regulation or transcriptional networks; however, functional blocking experiments should be independently verified.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio partners with diagnostic manufacturers, labs, and research institutes to streamline IVD raw material procurement—from initial screening to commercial-scale supply. This anti-TCF19 polyclonal antibody, targeting a key transcription factor in cell cycle control, exemplifies our commitment to providing validated antibody reagents for oncology and gene regulation research. Beyond individual antibodies, we offer integrated solutions including antibody pairs for immunoassay development, ancillary reagents, and custom sourcing for rare-target raw materials, all supported by dedicated technical consultation.