Anti-TBX22 Polyclonal Antibody for WB, ELISA - Q9Y458

Core Product Specifications and Parameters

Biological Background: TBX22 Function and Localization

• TBX22 is a T-box transcription factor encoded by the TBX22 gene, with known alternative splicing variants.
• It functions as a probable transcriptional regulator crucial for developmental processes, particularly palatogenesis (palate formation).
• TBX22 localizes to the nucleus where it binds DNA to regulate gene expression.
• It is a major determinant in cleft palate disorders, as indicated by disease variant associations in the keywords.
• Tissue expression appears to be low level, based on limited specificity data.
• Keywords associated with TBX22 include alternative splicing, disease variant, DNA-binding, nucleus, transcription regulation, and reference proteome.

Experimental Guidance and Technical Tips

• The immunogen used is a recombinant fusion protein covering amino acids 291-520, a region that may be conserved; assess cross-reactivity in your specific experimental setup.
• For WB, consider running a molecular weight marker at 58kDa and performing appropriate blocking and antibody titration; validate with positive control lysates.
• For ELISA, optimize coating antigen concentration and antibody dilution; include relevant controls for specificity.
• Cross-reactivity with human, mouse, and rat is reported; verify consistency in your sample species.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides one-stop access to premium IVD raw materials and supporting services for diagnostic manufacturers and research institutes. Our portfolio includes validated antibody pairs, optimized polyclonal antibodies like this anti-TBX22 reagent, and bulk ancillary reagents to accelerate your translational workflows. For rare target raw materials, we leverage extensive supply networks to support your entire development process from concept to clinic.