Anti-TAS1R1 Rabbit Polyclonal Antibody for WB and ELISA - Q7RTX1

Core Product Specifications and Parameters

Biological Background: TAS1R1 Function and Localization

• Encodes taste receptor type 1 member 1 (T1R1), also known as G protein-coupled receptor 70 (GPR70).
• Forms a heterodimeric receptor with TAS1R3 to mediate umami taste perception (the taste of monosodium glutamate).
• Belongs to the G protein-coupled receptor (GPCR) family and contains seven transmembrane domains.
• Localized to the cell membrane where it functions in gustatory signal transduction.
• Undergoes alternative splicing, generating multiple transcript variants.
• Post-translational modifications include N-linked glycosylation, typical of cell surface receptors.
• Sequence variations between species and individuals influence ligand selectivity and response sensitivity.

Experimental Guidance and Technical Tips

• The immunogen spans amino acids 330–567, targeting a region that may confer specificity across human, mouse, and rat homologs.
• For Western blot, a predominant band near 93 kDa is expected; additional bands may appear due to glycosylation or splice variants. Validate in taste bud‑enriched tissue or recombinant expression systems.
• In ELISA, consider using the antibody as either a coating or detection reagent; optimal working concentrations should be determined empirically in the relevant sample matrix.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as a dedicated one‑stop conduit for IVD raw‑material sourcing, connecting diagnostic manufacturers and research labs with validated antibody pairs, optimized polyclonal and monoclonal antibodies, bulk ancillary reagents, and rare‑target sourcing services. For gustatory research and GPCR‑focused assay development, we can leverage our network to supply TAS1R1 antibodies and related functional-grade reagents that align with your development pipeline. We invite you to discuss your specific raw‑material requirements with our team.