Anti-SYNPO Rabbit Polyclonal Antibody for WB, ELISA - Q8N3V7

Core Product Specifications and Parameters

Biological Background: Synaptopodin Function and Localization

• Synaptopodin (SYNPO) is an actin-associated protein that modulates actin-based shape and motility in dendritic spines and renal podocyte foot processes (By similarity).
• It is essential for the formation of spine apparatuses in telencephalic neurons, a structure critical for synaptic plasticity (By similarity).
• Synaptopodin localizes to the cytoplasm, cytoskeleton, cell junctions (tight junctions), perikaryon, dendritic spines, postsynaptic density, and synapse.
• Expression is detected in the cerebral cortex.
• The protein is subject to alternative splicing, acetylation, phosphorylation, and glycosylation.

Experimental Guidance and Technical Tips

• The immunogen peptide resides within amino acids 820–920 of human SYNPO (isoform NP_001159680.1). For western blotting, anticipate a band near 99 kDa and validate detection in your sample lysates.
• Because cross-reactivity is reported for human, mouse, and rat, consider verifying reactivity in the species-specific model system relevant to your study.
• For ELISA, optimize coating conditions and antibody dilution according to your assay format.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as a comprehensive sourcing partner for IVD raw materials, supporting researchers and diagnostic manufacturers from early development to clinical application. This SYNPO antibody is suited for investigations into synaptic biology and podocyte function. Through CamelBio, access validated antibody pairs, optimized polyclonal and monoclonal reagents, bulk ancillary reagents, and sourcing for rare targets to streamline your assay development.