Anti-SVOP Rabbit Polyclonal Antibody for WB, ELISA - Q8N4V2

Core Product Specifications and Parameters

Biological Background: SVOP Function and Localization

• Synaptic vesicle 2-related protein (SVOP) is encoded by the SVOP gene, with alias SLC22B4.
• Predicted to be an integral membrane protein containing multiple transmembrane helices (keyword: Transmembrane helix).
• Localizes to cytoplasmic vesicle, secretory vesicle, and synaptic vesicle membrane (keyword: Cytoplasmic vesicle, Synapse).
• Post-translationally modified by phosphorylation (keyword: Phosphoprotein), which may regulate its activity or interactions.
• Associated with transport functions (keyword: Transport), suggesting a role in moving substrates across the vesicular membrane.
• Identified through proteomics analysis (keyword: Proteomics identification) and considered part of the reference human proteome (keyword: Reference proteome).
• The calculated molecular weight of the human protein is approximately 60.8 kDa, consistent with the product specification.
• Given its synaptic localization and membrane topology, SVOP may participate in synaptic vesicle dynamics or neurotransmitter release mechanisms.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal 80 amino acids of human SVOP, indicating the antibody likely recognizes epitopes in this region. Confirm specificity using a control antigen or lysate from SVOP-overexpressing cells.
• For Western Blot (WB) analysis, consider testing a range of primary antibody dilutions (e.g., 1:500–1:2000) and optimizing blocking, incubation times, and detection steps according to your experimental system.
• For ELISA applications, both direct and indirect formats can be employed. Titrate the antibody and standardize coating concentrations to achieve linear detection and minimal background.
• Cross-reactivity is validated for human samples. Performance in other species is not guaranteed and should be verified independently if required.
• As a polyclonal antibody, lot-to-lot consistency may vary. Include appropriate positive and negative controls in every experiment, and consider re-validating after prolonged storage.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your trusted one‑stop partner for IVD raw materials, offering a comprehensive selection of high-quality antibodies, antigens, and ancillary reagents. Our SVOP rabbit polyclonal antibody supports neuroscience and membrane transport research, enabling seamless assay development from early discovery to clinical validation. With our expert technical support and global supply chain, we help accelerate your diagnostic projects.