Anti-STK24 Polyclonal Antibody for WB, IHC-P, IF/ICC, ELISA - Q9Y6E0

Core Product Specifications and Parameters

Biological Background: STK24 Function and Localization

• STK24 (Mammalian STE20-like protein kinase 3) is a serine/threonine kinase that promotes apoptosis in response to stress and caspase activation.
• Mediates oxidative-stress-induced cell death by phosphorylating JNK and p38 MAP kinases, and participates in a staurosporine-induced caspase-independent pathway.
• Regulates cellular migration: phosphorylates PTPN12 to inhibit its activity and may affect paxillin phosphorylation; also negatively regulates Golgi reorientation in polarized migration via association with STK26. Related references: PMID:27807006
• Key component of the STRIPAK complex, critical for regulating Hippo, MAPK, and cytoskeleton signaling. Related references: PMID:18782753
• Localizes to the cytoplasm, nucleus, and membrane.
• Isoform A is ubiquitously expressed; isoform B is enriched in brain (hippocampus and cerebral cortex).
• Annotated with keywords including ATP-binding, kinase, apoptosis, alternative splicing, and phosphoprotein.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the C-terminal region (aa 312-431) of human STK24; consider using full-length protein controls to confirm specificity.
• Recommended applications include WB (predicted MW ~49 kDa), IHC-P, IF/ICC, and ELISA. Validate in your specific sample system, as performance may vary with tissue/cell type.
• Cross-reacts with human, mouse, and rat; verify reactivity in other species if needed.
• Shipped on ice bag; for optimal stability, store aliquots at -20°C and avoid repeated freeze-thaw cycles.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as your single-window sourcing partner for IVD raw materials, offering a comprehensive portfolio of validated antibodies, including this anti-STK24 polyclonal antibody tailored for apoptosis and cell signaling research. We support diagnostic manufacturers and research institutes with bulk ancillary reagents, custom antibody development, and procurement of rare-target raw materials to accelerate project timelines. Partner with us for streamlined access to high-quality immunoassay components from discovery through clinical application.