Anti-SRPRB Rabbit Polyclonal Antibody for WB, IF/ICC, ELISA - Q9Y5M8

Core Product Specifications and Parameters

Biological Background: SRPRB Function and Localization

• Encodes signal recognition particle receptor subunit beta, also designated protein APMCF1 (Alt Names).
• Acts as a core component of the SRP complex receptor (SR). Together with the SRP complex, it ensures accurate targeting of nascent secretory proteins to the endoplasmic reticulum membrane system.
• May facilitate the membrane association of SR, promoting efficient protein translocation.
• Localizes to the endoplasmic reticulum membrane, consistent with its role in co‑translational translocation.
• Classified as a receptor with GTP‑binding and nucleotide‑binding properties; annotated as a phosphoprotein and a transmembrane helix‑containing protein.
• Mol Weight: 29702 Da (UniProt).

Experimental Guidance and Technical Tips

• The immunogen encompasses amino acids 57–271 of human SRPRB (NP_067026.3); verify specificity in the relevant sample system.
• For Western blotting, a band around 30 kDa is expected; consider enrichment of membrane fractions to improve signal.
• For IF/ICC, validate ER localization using appropriate counterstains and controls.
• This antibody is predicted to cross‑react with human, mouse, and rat SRPRB; confirm performance for your species of interest.
• Optimize dilutions for ELISA based on the conjugate and coating conditions used.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, labs, and research institutes with one‑stop access to IVD raw materials, technical services, and consulting—covering every stage from concept to clinic. This anti‑SRPRB antibody supports investigations into protein targeting and endoplasmic reticulum transport, a focus area for numerous therapeutic developments. Our supply capabilities include validated antibody pairs, bulk ancillary reagents, and custom sourcing for rare‑target raw materials.