Anti-SNRNP40 Polyclonal Antibody for WB, ELISA - Q96DI7

Core Product Specifications and Parameters

Biological Background: SNRNP40 Function and Localization

• SNRNP40 (U5 snRNP 40kDa protein, WDR57, PRP8BP) is a WD repeat-containing spliceosomal protein.
• Required for pre-mRNA splicing as a component of the activated spliceosome. Related references: PMID:11991638, PMID:28076346, PMID:28502770
• Component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Related references: PMID:16723661, PMID:26912367, PMID:9774689
• Involved in splicing of U12-type introns in pre-mRNAs (Probable).
• Predominantly localizes to the nucleus.
• Features WD repeats, methylation, and isopeptide bond modifications; subject to alternative splicing.
• Endogenous protein has a molecular weight of ~39 kDa.

Experimental Guidance and Technical Tips

• The immunogen spans the N-terminal 357 amino acids, covering multiple WD repeats; this may help detect various isoforms or modifications.
• For Western blot, consider using whole cell lysates from human, mouse, or rat cell lines; an expected band is observed at ~39-40 kDa.
• Validate the antibody in your specific sample system, and consider nuclear extraction protocols if enhanced signal is needed.
• For ELISA, testing with recombinant protein or peptide is advisable to confirm reactivity and titer under your conditions.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers comprehensive access to IVD raw materials for spliceosome and splicing research. Beyond this SNRNP40 polyclonal antibody, we supply validated antibody pairs, optimized monoclonal antibodies, bulk ancillary reagents, and rare-target raw-material sourcing. Our team can also provide technical consultation to support your assay development from concept to clinic.