Anti-SLTM Rabbit Polyclonal Antibody for WB, ELISA - Q9NWH9

Core Product Specifications and Parameters

Biological Background: SAFB-like transcription modulator Function and Localization

• SLTM (SAFB-like transcription modulator), also referred to as modulator of estrogen-induced transcription, functions as a general inhibitor of transcription when overexpressed, ultimately triggering apoptosis.
• The protein localizes to the nucleus, consistent with its role in transcriptional regulation and apoptotic signaling.
• Post-translational modifications include acetylation, methylation, phosphorylation, and ubiquitination, indicating dynamic regulatory control.
• Structural features include a coiled-coil domain and RNA-binding capability, suggesting involvement in protein–protein and protein–RNA interactions.
• Alternative splicing generates multiple transcript variants, expanding functional diversity.
• SLTM has been identified through proteomic approaches, confirming endogenous expression.

Experimental Guidance and Technical Tips

• The immunogen spans amino acids 900–1000 within the C-terminal region of human SLTM; the antibody may recognize full-length and partially truncated isoforms containing this epitope.
• For Western blot, a predominant band near 117 kDa is expected; consider validating detection in the relevant sample system.
• Cross-reactivity with mouse has been observed; experimental conditions should be optimized when working with mouse tissue or cell lysates.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and researchers with streamlined access to IVD raw materials, supporting projects from concept to clinic. This anti-SLTM polyclonal antibody serves transcription and apoptosis research, and CamelBio can also supply validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare-target raw materials to accelerate your assay development.