Anti-SLC44A1 Polyclonal Antibody for WB, ELISA - Q8WWI5

Core Product Specifications and Parameters

Biological Background: Choline Transporter-Like Protein 1 (SLC44A1) Function and Localization

• SLC44A1, also known as CD92, CTL1, or CDW92, is a choline transporter-like protein 1 belonging to the solute carrier family 44.
• Functions as a choline/H+ antiporter, mediating the uptake of choline into cells (PubMed:19357133, PubMed:23651124, PubMed:31855247). Related references: PMID:19357133 | PMID:23651124 | PMID:31855247
• Acts as a high-affinity ethanolamine/H+ antiporter, regulating extracellular ethanolamine supply for the CDP-ethanolamine pathway and balancing the CDP-choline and CDP-ethanolamine arms of the Kennedy pathway (PubMed:33789160). Related references: PMID:33789160
• Involved in membrane synthesis and myelin production (PubMed:31855247). Related references: PMID:31855247
• Localizes to the cell membrane and the mitochondrial outer membrane.
• Expressed in various cells of the hematopoietic system.
• Annotated with keywords including alternative splicing, antiport, lipoprotein, transmembrane, myristate, phosphoprotein, and neurodegeneration.

Experimental Guidance and Technical Tips

• For Western blot (WB), expect a band near 73 kDa; optimize antibody dilution and blocking conditions for your sample type.
• In ELISA, validate with recombinant SLC44A1 protein or lysates from human, mouse, or rat tissues to confirm reactivity.
• Since the immunogen corresponds to amino acids 55–210, the antibody may detect multiple isoforms or processed forms; consider using knockout controls or pre-adsorption experiments to confirm specificity.
• Test cross-reactivity with other species if needed, as it has been reported to react with human, mouse, and rat.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers, labs, and research institutes comprehensive access to IVD raw materials, including validated antibody pairs, optimized monoclonal and polyclonal antibodies, and bulk ancillary reagents. This anti-SLC44A1 polyclonal antibody supports studies on choline transport and membrane synthesis, and our team can assist with sourcing rare-target raw materials or custom antibody development. Partner with CamelBio to streamline your workflow from concept to clinic.