Anti-SLC34A2 Polyclonal Antibody for WB and ELISA - O95436

Core Product Specifications and Parameters

Biological Background: SLC34A2 Function and Localization

• SLC34A2 encodes the sodium-dependent phosphate transport protein 2B, also known as NaPi-2b or NaPi3b, a member of the solute carrier family 34.
• It functions as a Na+–Pi symporter, actively importing phosphate ions into cells using the sodium electrochemical gradient.
• The protein localizes to the apical cell membrane, facilitating vectorial phosphate absorption across epithelia.
• Highly expressed in the lung, specifically in alveolar type II cells; also detected in pancreas, kidney, small intestine, ovary, testis, prostate, and mammary gland.
• Post-translational modifications include glycosylation and disulfide bonds; the protein contains multiple transmembrane helices.
• Alternative splicing generates different isoforms of SLC34A2.
• UniProt annotates SLC34A2 with the keyword "Disease variant," indicating its involvement in human disease.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 234-362 of human SLC34A2; the resulting polyclonal antibody is suitable for Western blot (WB) and ELISA applications.
• Given the reported cross-reactivity with mouse and rat, this antibody can be used for comparative studies; users should validate performance in their specific sample matrices.
• For WB, consider testing lysates from tissues with high SLC34A2 expression, such as lung or kidney, to confirm specificity.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research labs with a single point of access to IVD raw materials, from validated antibodies like this anti-SLC34A2 pAb to bulk ancillary reagents and rare target sourcing. Supporting studies of phosphate transport and pulmonary biology, CamelBio streamlines procurement so you can move from concept to clinic efficiently. Contact us to explore your entire assay development needs.