Anti-SLC2A5 (GLUT5) Rabbit Polyclonal Antibody for WB, ELISA - P22732

Core Product Specifications and Parameters

Biological Background: SLC2A5 Function and Localization

• SLC2A5 functions as a fructose transporter with low affinity for other monosaccharides. Related references: PMID:16186102 PMID:17710649 PMID:28083649 PMID:1695905
• It is essential for fructose uptake in the small intestine and plays a role in dietary fructose-induced blood pressure regulation (By similarity).
• Detected at the protein level in jejunum brush border and basolateral membranes, skeletal muscle, and at lower levels in kidney and adipose tissue. Related references: PMID:7619085
• Localizes to the apical cell membrane, sarcolemma, and cell membrane.
• Post-translationally modified by acetylation and glycosylation.
• Alternative splicing yields multiple isoforms, which may have distinct functional properties.
• Belongs to the major facilitator superfamily, solute carrier 2A family, with a predicted molecular weight of ~55 kDa.

Experimental Guidance and Technical Tips

• The immunogen is a synthetic peptide from the N-terminal region (aa 1-100) of human SLC2A5; this region may be conserved across species, supporting the observed cross-reactivity with mouse.
• For WB, consider using whole-cell lysates from tissues known to express SLC2A5, such as small intestine or skeletal muscle, to validate antibody specificity.
• For ELISA, the peptide immunogen can serve as a positive control to assess antibody binding affinity.
• Given the ~55 kDa predicted mass and potential glycosylation, a band shift might be observed; include appropriate molecular weight markers.
• As a polyclonal antibody, batch-to-batch variability may occur; include appropriate controls and optimize dilution for each application.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research institutes with one-stop access to IVD raw materials, technical services, and consulting—covering every stage from concept to clinic. This anti-SLC2A5 polyclonal antibody supports research in fructose metabolism and transporter studies, and we can assist with large-scale procurement of validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare target raw-material sourcing. Our supply capabilities are designed to streamline your development pipeline without compromising on quality or timelines.