Anti-SLC27A6 Polyclonal Antibody for WB and ELISA - Q9Y2P4

Core Product Specifications and Parameters

Biological Background: SLC27A6 Function and Localization

• SLC27A6 (Long-chain fatty acid transport protein 6), also known as FATP6, ACSVL2, FACVL2, and VLCS-H1, is a member of the solute carrier family 27 (SLC27) and functions as a fatty acid transporter and acyl-CoA ligase.
• It facilitates the import of long-chain fatty acids (LCFA) at the plasma membrane and catalyzes the ATP-dependent formation of fatty acyl-CoA from LCFA and very-long-chain fatty acids (VLCFA), playing a critical role in lipid metabolism (PubMed:12556534). Related references: PMID:12556534
• SLC27A6 is highly expressed in the heart, where it localizes to cardiac myocytes and supports beta-oxidation by regulating exogenous LCFA substrate availability. It is also expressed at moderate levels in placenta, testis, and adrenal glands, and at low levels in kidney, bladder, and uterus.
• The protein is primarily localized to the cell membrane and sarcolemma, consistent with its role in transmembrane fatty acid transport.
• According to UniProt keywords, SLC27A6 is involved in fatty acid metabolism, lipid transport, and nucleotide binding, and it is a transmembrane protein with a molecular weight of approximately 70 kDa.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 370–619 of human SLC27A6; consider verifying reactivity with your target region if studying specific isoforms or domains.
• For Western blot, the predicted molecular weight is ~70 kDa. A band of this size may be observed in human and mouse lysates, particularly in heart tissue, where expression is highest. Validate with appropriate positive controls.
• This antibody is suitable for ELISA; ensure proper coating and detection conditions are optimized in your assay setup.
• Cross-reactivity is reported for human and mouse; if using samples from other species, confirm specificity experimentally.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is a dedicated sourcing partner for IVD manufacturers and researchers, offering a comprehensive portfolio of raw materials for lipid metabolism and fatty acid transport studies. We provide validated antibody pairs, optimized polyclonal and monoclonal antibodies, and bulk ancillary reagents to streamline your assay development. For challenging or rare targets like SLC27A6, our team can assist with raw-material sourcing and technical consulting from concept through clinical application.