Anti-SLC25A43 Polyclonal Antibody for WB, ELISA - Q8WUT9

Core Product Specifications and Parameters

Biological Background: SLC25A43 Function and Localization

• Solute carrier family 25 member 43 (SLC25A43) belongs to the mitochondrial carrier family, a large group of proteins responsible for transporting metabolites, nucleotides, and cofactors across the inner mitochondrial membrane.
• The protein is localized to the mitochondrial inner membrane, as annotated in UniProtKB/Swiss-Prot.
• It is predicted to contain six transmembrane helices, a structural hallmark of mitochondrial carrier proteins.
• Alternative splicing generates multiple transcript variants, increasing functional diversity.
• Based on family homology, SLC25A43 is presumed to function as a transporter, though its specific substrate remains uncharacterized.
• Proteomic studies have confirmed its expression at the protein level, supporting its biological relevance.

Experimental Guidance and Technical Tips

• The immunogen is a synthetic peptide from the N-terminal region (amino acids 1–100); verify specificity using appropriate controls such as knockout or knockdown lysates.
• For Western blot, a band around 38 kDa is expected; optimize primary antibody dilution and detection conditions in your sample type.
• In ELISA, titrate the antibody against recombinant or native protein to establish optimal working concentrations.
• Polyclonal antibodies may exhibit lot-to-lot variation; consider validating each new batch in your assay system.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research laboratories with one-stop access to IVD raw materials, including validated antibody pairs, optimized monoclonal and polyclonal antibodies, and bulk ancillary reagents. For studies focused on mitochondrial transporters, we can source rare-target antibodies and assist with customized reagent development. Our supply chain expertise helps streamline your transition from concept to clinic.