Anti-SLC25A17 Polyclonal Antibody for WB, IF/ICC, ELISA - O43808

Core Product Specifications and Parameters

Biological Background: SLC25A17 Function and Localization

• SLC25A17, also known as PMP34 or solute carrier family 25 member 17, encodes a 34 kDa peroxisomal membrane protein.
• It functions as a peroxisomal transporter for multiple cofactors, including coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN), and adenosine monophosphate (AMP).
• The transporter also exhibits lower affinity for nicotinamide adenine dinucleotide (NAD+), adenosine diphosphate (ADP), and adenosine 3',5'-diphosphate (PAP), operating via a counter-exchange mechanism.
• SLC25A17 belongs to the mitochondrial carrier family and contains several transmembrane helices typical of this family.
• It localizes primarily to the peroxisomal membrane and is also found in the cytoplasm.
• Expression is ubiquitous, with notable presence in the liver tissue.

Experimental Guidance and Technical Tips

• The antibody was raised against a synthetic peptide from residues 150–250 of human SLC25A17; for Western blot, anticipate a band near 35 kDa and validate using a suitable positive control (e.g., human liver lysate).
• For immunofluorescence (IF/ICC), include a permeabilization step to allow antibody access to the peroxisomal membrane target; consider co-staining with a peroxisomal marker.
• In ELISA assays, the immunizing peptide can serve as a positive control; optimize antigen coating and antibody dilution for your specific system.
• While the antibody is reported to react with human and mouse SLC25A17, cross-reactivity with other species should be tested individually.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is a dedicated one-stop source for IVD raw materials, offering this SLC25A17 polyclonal antibody as part of a comprehensive portfolio that includes validated antibody pairs, optimized monoclonal and polyclonal antibodies, and bulk ancillary reagents. Whether you need standard or rare-target antibodies for peroxisome biology, CamelBio’s supply chain expertise helps streamline your research and diagnostic development from concept to clinic.