Anti-SLC24A4 Rabbit Polyclonal Antibody for WB and ELISA - Q8NFF2

Core Product Specifications and Parameters

Biological Background: SLC24A4 Function and Localization

• Functions as a calcium, potassium:sodium antiporter, exchanging 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) (PubMed:12379639, PubMed:26631410). Related references: PMID:12379639 PMID:26631410
• Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons, influencing how odor information is encoded and perceived (By similarity).
• May play a role in calcium transport during amelogenesis (PubMed:23375655, PubMed:24621671). Related references: PMID:23375655 PMID:24621671
• Localizes to the cell membrane and cytoplasm.
• Expressed abundantly in all regions of the brain, aorta, lung and thymus; expressed at lower levels in stomach and intestine (PubMed:12379639). Related references: PMID:12379639
• Exhibits alternative splicing and is associated with disease variants including amelogenesis imperfecta.
• Belongs to the solute carrier family 24 and contains transmembrane helices; annotated with keywords including antiport, ion transport, sensory transduction, and glycoprotein.

Experimental Guidance and Technical Tips

• The immunogen is a synthetic peptide within residues 200–300 of human SLC24A4; consider using the corresponding peptide as a blocking control to confirm specificity.
• For Western blotting, optimize antibody dilution using positive control lysates from brain tissues (human, mouse, or rat), where SLC24A4 is highly expressed.
• In ELISA, direct detection of the immunizing peptide or recombinant SLC24A4 may be feasible; validate coating and detection parameters empirically.
• As a polyclonal antibody, inter-batch consistency should be verified with internal reference standards; cross-reactivity with other SLC24 family members cannot be fully excluded.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research labs with a streamlined sourcing channel for IVD-grade antibodies, antigens, and ancillary reagents. This anti-SLC24A4 polyclonal antibody supports investigations into calcium signaling, olfaction, and dental development. From bulk orders to custom formulation and rare target raw-material procurement, CamelBio is equipped to bridge your concept-to-clinic needs efficiently.