Anti-SERPINA12 Polyclonal Antibody for WB, ELISA - Q8IW75

Core Product Specifications and Parameters

Biological Background: SERPINA12 Function and Localization

• SERPINA12, also known as Vaspin (visceral adipose tissue-derived serine protease inhibitor), OL-64, or visceral adipose-specific serpin, is a member of the serpin superfamily.
• It functions as an adipokine that modulates insulin action by specifically inhibiting the serine protease KLK7 in white adipose tissues.
• Expression is predominantly in visceral adipose tissues, highlighting its role in metabolic regulation.
• The protein is secreted into the extracellular space.
• SERPINA12 is classified as a glycoprotein and serine protease inhibitor, with a signal peptide indicating its secretory nature.
• A 3D-structure has been determined, and the protein is part of the reference proteome.

Experimental Guidance and Technical Tips

• The immunogen covers amino acids 20–320 of the human SERPINA12 protein; consider using the corresponding peptide as a blocking agent in competition assays.
• For Western blotting, a band around 47 kDa is expected; validate in the relevant sample system, such as visceral adipose tissue lysates.
• ELISA performance can be optimized by using recombinant SERPINA12 as a standard; cross-reactivity with mouse may require sequence alignment verification.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your one-stop sourcing partner for IVD raw materials, offering validated antibodies and ancillary reagents to support research on SERPINA12 and visceral adipose tissue biology. With a focus on diagnostic manufacturing, we provide optimized monoclonal/polyclonal antibodies, antigen-grade recombinant proteins, and bulk raw materials to streamline your assay development. Whether you need rare-target sourcing or comprehensive supply solutions, CamelBio bridges the gap from concept to clinic.