Anti-SERPINA10 Rabbit Polyclonal Antibody for WB, IHC-P, ELISA - Q9UK55

Core Product Specifications and Parameters

Biological Background: SERPINA10 (Protein Z-dependent protease inhibitor) Function and Localization

• Protein Z-dependent protease inhibitor (Serpin A10), encoded by the SERPINA10 gene, is a member of the serpin superfamily of serine protease inhibitors.
• Inhibits coagulation factor Xa in a calcium- and phospholipid-dependent manner, requiring protein Z as a cofactor; also inhibits factor XIa independently of cofactors.
• Secreted protein primarily expressed by the liver and released into plasma.
• Plays a key role in the regulation of blood coagulation and hemostasis.
• Contains heparin-binding and phosphorylation sites; classified as a glycoprotein.

Experimental Guidance and Technical Tips

• For Western blot, the immunogen targets the serpin domain (aa 165–444); consider using a reducing gel and standard blocking conditions, and validate with liver or plasma lysates where protein expression is expected.
• For IHC-P, antigen retrieval may be necessary; test on liver tissue sections as a positive control.
• The antibody cross-reacts with mouse and rat, enabling multispecies studies; validate detection in the relevant sample system before use.
• As a polyclonal antibody, monitor lot-to-lot consistency and consider including a positive control antigen in experiments.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your one-stop sourcing bridge for IVD raw materials, providing validated antibodies and reagents for coagulation research. In addition to this SERPINA10 antibody, we supply optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and custom sourcing for rare targets like coagulation proteases and inhibitors. Streamline your diagnostic development with our comprehensive procurement solutions.