Anti-Septin-1 Polyclonal Antibody for WB, IHC-P, ELISA - Q8WYJ6

Core Product Specifications and Parameters

Biological Background: Septin-1 Function and Localization

• Septin-1, also known as LARP, Peanut-like protein 3, or serologically defined breast cancer antigen NY-BR-24, is a member of the septin family of filament-forming GTPases.
• It functions as a cytoskeletal GTPase and may play a role in cytokinesis, the final stage of cell division.
• Septin-1 localizes to the cytoplasm and associates with cytoskeletal structures, including the centrosome and midbody, consistent with its role in cell division.
• The protein is highly expressed in lymphoid and hematopoietic tissues, suggesting specialized functions in these systems.
• Alternative splicing generates multiple isoforms, and the protein undergoes phosphorylation, which may regulate its activity.
• Keywords from UniProt indicate involvement in cell cycle, cell division, and GTP-binding, highlighting its importance in fundamental cellular processes.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 270-370 in the C-terminal region of human Septin-1 (NP_443070.5). Ensure the target protein is full-length when using this antibody.
• Recommended applications based on supplier specifications are WB, IHC-P, and ELISA; consider validating in the relevant sample system.
• For IHC-P, appropriate antigen retrieval methods and permeabilization may be required to detect the cytoskeleton-associated protein effectively.
• As the antibody recognizes human, mouse, and rat Septin-1, it is suitable for cross-species studies; verify reactivity in your experimental model.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research laboratories with a streamlined procurement pathway for IVD raw materials, including validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and rare-target sourcing. This polyclonal antibody targeting Septin-1 supports studies in cell division and cytoskeleton dynamics, complementing CamelBio’s comprehensive portfolio. Whether you need customized antibody development or reliable supply of core raw materials from concept to clinic, CamelBio serves as your dedicated sourcing partner.