Anti-SEMG2 Rabbit Polyclonal Antibody for WB, ELISA - Q02383

Core Product Specifications and Parameters

Biological Background: Semenogelin-2 Function and Localization

• Semenogelin-2 (SEMG2), also known as Semenogelin II (SGII), is a glycoprotein encoded by the SEMG2 gene in humans.
• It participates in the formation of a gel matrix (sperm coagulum) that entraps accessory gland secretions and ejaculated spermatozoa.
• SEMG2 is primarily expressed in seminal vesicles, with much lower expression in the epididymis.
• The protein contains repetitive sequence elements and is classified as a secreted protein with a signal peptide.
• With a molecular weight of approximately 65 kDa (UniProt: 65444 Da), SEMG2 is a key component of semen coagulation, relevant to reproductive biology.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the conserved C-terminal region (aa 383–582) of human SEMG2, supporting cross-reactivity with mouse samples.
• For western blot, a major band around 65 kDa is expected in seminal vesicle lysates; consider using reducing conditions to resolve potential aggregates.
• In ELISA applications, validate the antibody as a capture or detection reagent in the relevant biological matrix (e.g., seminal plasma).
• Optimize dilutions for each assay and sample type to achieve the desired specificity and signal intensity.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides one-stop access to high-quality IVD raw materials, including the Anti-SEMG2 Rabbit Polyclonal Antibody for reproductive health and fertility research. Our global supply network delivers validated antibodies, bulk ancillary reagents, and customized raw-material sourcing to accelerate your diagnostic development from concept to clinic.