Anti-SCRN3 Rabbit Polyclonal Antibody for WB, IF/ICC, ELISA - Q0VDG4

Core Product Specifications and Parameters

Biological Background: SCRN3 Function and Localization

• SCRN3 (Secernin-3) is a protein encoded by the SCRN3 gene in humans (Gene ID: 79634), also known as SES3.
• It plays a role in thermal nociception, the sensory perception of painful heat stimuli.
• The gene undergoes alternative splicing, producing multiple transcript variants.
• Identified in large-scale proteomics studies, indicating broad expression or functional relevance.
• Associated with pyruvate metabolism, as indicated by UniProt keyword annotation.
• The protein has a molecular weight of approximately 49 kDa (calculated 48.5 kDa).

Experimental Guidance and Technical Tips

• The immunogen corresponds to the central region of SCRN3 (amino acids 100–410), which may provide specificity for detecting endogenous SCRN3.
• For Western blot (WB), consider using a starting dilution in the range of 1:500–1:2000 and validate with appropriate positive controls expressing SCRN3.
• Immunofluorescence/immunocytochemistry (IF/ICC) may require optimization of fixation and permeabilization conditions; include a no-primary antibody control.
• Cross-reactivity with mouse and rat suggests conserved epitopes, but performance in these species should be independently validated with relevant samples.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your trusted one-stop partner for IVD raw materials, offering validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare target sourcing. This anti-SCRN3 polyclonal antibody supports research into thermal nociception and related pathways. Leverage our supply network to accelerate your diagnostic development from concept to clinic.