Anti-SCCPDH Rabbit Polyclonal Antibody for WB, ELISA - Q8NBX0

Core Product Specifications and Parameters

Biological Background: SCCPDH Function and Localization

• SCCPDH (NET11, CGI-49) encodes a saccharopine dehydrogenase-like oxidoreductase, as annotated in UniProt (Q8NBX0).
• The protein has been experimentally identified through proteomics and direct protein sequencing, confirming its endogenous expression.
• Post-translational modifications include acetylation and phosphorylation (UniProt keywords), which may influence its activity or interactions.
• It belongs to a putative oxidoreductase family related to saccharopine dehydrogenase, though its specific enzymatic function remains uncharacterized in the reviewed entry.
• The predicted molecular weight is approximately 47.1 kDa, consistent with the observed 47 kDa in experimental applications.
• No subcellular localization, tissue specificity, or functional details are available in the current Swiss-Prot record.

Experimental Guidance and Technical Tips

• The immunogen spans the full N-terminal region (aa 1-270), suggesting potential recognition of multiple epitopes; validate specificity using blocking peptides or knockout controls if available.
• For Western blot, consider a starting dilution range (e.g., 1:500–1:2000) and optimize using lysates from human or mouse cell lines expressing SCCPDH.
• In ELISA, pair with a suitable detection antibody and titrate both coating antigen and antibody concentrations to achieve optimal signal.
• Cross-reactivity with mouse indicates utility for rodent model studies; confirm performance in your specific experimental system.
• As a polyclonal antibody, lot-to-lot consistency should be verified for quantitative assays.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio connects diagnostic manufacturers, laboratories, and research institutes with comprehensive IVD raw-material solutions. For SCCPDH and oxidoreductase research, we supply validated antibody pairs, optimized recombinant proteins, and bulk ancillary reagents tailored to your assay development needs. Explore our one-stop sourcing platform to accelerate your project from concept to clinic with reliable, research-ready materials.