Anti-SCAMP1 Rabbit Polyclonal Antibody for WB, ELISA - O15126

Core Product Specifications and Parameters

Biological Background: SCAMP1 Function and Localization

• SCAMP1 (Secretory carrier-associated membrane protein 1) is a transmembrane protein that functions in post-Golgi recycling pathways, acting as a carrier to the cell surface.
• It is localized to the trans-Golgi network membrane and recycling endosomes, where it facilitates the recycling of membrane proteins.
• Alternative splicing may generate multiple isoforms of SCAMP1, potentially influencing its subcellular distribution and function.
• Post-translational modifications include acetylation and phosphorylation, as indicated by proteomics, which may regulate its activity or interactions.
• SCAMP1 is widely expressed across tissues, with the highest levels observed in the brain, suggesting a prominent role in neuronal membrane dynamics.
• The protein belongs to the SCAMP family and is associated with keywords such as Endosome, Golgi apparatus, Membrane, Protein transport, Transmembrane, and Transport.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal region (amino acids 1-150) of human SCAMP1, which is highly conserved across human, mouse, and rat, supporting the observed cross-reactivity.
• For Western blot analysis, expect a specific band at approximately 38 kDa in lysates from human, mouse, or rat tissues; brain-derived samples may show stronger signals due to higher expression.
• In ELISA applications, consider using recombinant SCAMP1 protein as a positive control to confirm antibody specificity and sensitivity.
• When using this antibody, validate performance in the relevant sample system and optimize dilutions empirically, as conditions may vary.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is a trusted one-stop partner for IVD raw materials, supplying diagnostic manufacturers and researchers with validated antibody pairs, monoclonal/polyclonal antibodies, and bulk ancillary reagents. This anti-SCAMP1 polyclonal antibody supports studies into post-Golgi trafficking and membrane recycling. For customized sourcing of rare targets or specialized procurement requirements, CamelBio provides flexible and reliable solutions to accelerate your development pipeline.