Anti-Sall4 Polyclonal Antibody for WB, IF-P, IHC-P, ELISA - Q9UJQ4

Core Product Specifications and Parameters

Biological Background: Sall4 Function and Localization

• Sall4, also known as Sal-like protein 4 or zinc finger protein 797, is a transcription factor belonging to the spalt-like family of zinc finger proteins.
• It plays a critical role in the maintenance and self-renewal of embryonic and hematopoietic stem cells.
• Sall4 is localized to both the nucleus and cytoplasm, consistent with its transcriptional regulatory function.
• Tissue expression is primarily observed in testis, and it is constitutively expressed in acute myeloid leukemia (AML), highlighting its role in oncogenesis.
• The protein contains multiple zinc-finger domains for DNA binding and is subject to post-translational modifications including phosphorylation and ubiquitination (isopeptide bond).
• Alternative splicing produces multiple isoforms, and it is classified as an oncogene and a disease-associated protein for conditions such as deafness.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 853-1053, a region likely exposed in native protein; consider this for detection of multiple isoforms.
• For WB, a prominent band around 112 kDa is expected; validate with appropriate controls in human, mouse, or rat samples.
• IF-P and IHC-P may require antigen retrieval and nuclear/cytoplasmic staining patterns should be anticipated.
• ELISA performance may vary; optimization of coating and detection conditions is recommended.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, labs, and research institutes with one-stop access to IVD raw materials, technical services, and consulting. For Sall4 research, we support procurement of validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare target raw-material sourcing. Our supply capabilities span from concept to clinic, ensuring reliable material access for your stem cell and oncology applications.