Anti-S100A11 Rabbit Polyclonal Antibody [KO Validated] for WB, IF/ICC, IP, ELISA - P31949

Core Product Specifications and Parameters

Biological Background: S100A11 Function and Localization

• S100A11 (also known as calgizzarin, MLN70, or S100-C) is a member of the S100 family of calcium-binding proteins.
• The protein plays a role in facilitating the differentiation and cornification of keratinocytes.
• S100A11 localizes to both the cytoplasm and nucleus.
• Post-translational modifications include acetylation, phosphorylation, and disulfide bond formation.
• It contains calcium-binding EF-hand repeats.
• The protein has a molecular weight of approximately 12 kDa (UniProt: 11740 Da).

Experimental Guidance and Technical Tips

• This antibody was raised against the full-length human S100A11 protein (aa 1-105) and may detect endogenous S100A11 in human samples.
• For Western blotting, the predicted band size is around 12 kDa; consider using a high-resolution gel and optimised transfer conditions.
• For immunofluorescence (IF/ICC), S100A11 exhibits both cytoplasmic and nuclear localisation; ensure appropriate fixation and permeabilisation protocols.
• Validate the antibody in your specific experimental system using a relevant negative control (e.g., S100A11 knockout cell lysates).
• The antibody is also suitable for immunoprecipitation (IP) and ELISA applications; consider titrating and confirming performance in your assay conditions.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your trusted one-stop partner for IVD raw materials, offering comprehensive support from concept to clinic. For researchers studying keratinocyte biology, epithelial differentiation, or calcium-binding protein function, this anti-S100A11 antibody is backed by CamelBio's robust supply chain, including validated antibody pairs, optimised polyclonal antibodies, and bulk ancillary reagents. Whether you need routine catalog products or rare target raw-material sourcing, CamelBio streamlines your procurement with technical consulting and integrated logistics.