Anti-S100A10 Monoclonal Antibody for WB, IHC-P, ELISA - P60903

Core Product Specifications and Parameters

Biological Background: S100A10 Function and Localization

• Protein S100-A10 (also known as p11, calpactin I light chain) is a member of the S100 family of calcium-binding proteins.
• It functions as a critical regulator of annexin A2 (ANXA2) by inducing its dimerization, a process that may modulate protein phosphorylation.
• The interaction between S100A10 and ANXA2 is implicated in various cellular processes, including membrane organization and signal transduction.
• Post-translational modifications of S100A10 include acetylation, isopeptide bond formation, and ubiquitin-like conjugation.
• The molecular weight of S100A10 is approximately 11 kDa.

Experimental Guidance and Technical Tips

• Given the small molecular weight of S100A10 (~11 kDa), use high-percentage SDS-PAGE gels and low-molecular-weight markers for optimal separation in Western blotting.
• For immunohistochemistry (IHC-P), consider appropriate antigen retrieval methods and validate antibody specificity in human tissue sections.
• In ELISA applications, the antibody may be used as a capture or detection reagent; perform cross-validation to confirm its performance in your specific assay format.
• Since the immunogen is a synthetic peptide spanning the N-terminal region, the antibody is expected to recognize both native and denatured S100A10.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as a comprehensive IVD raw-material partner, connecting diagnostic manufacturers and research laboratories with high-quality reagents. For studies on S100A10 and ANXA2-related phosphorylation pathways, we offer validated monoclonal antibodies, matched antibody pairs, and bulk ancillary materials to streamline your assay development. Leverage our supply network to efficiently source even rare-target raw materials for your diagnostic needs.