Anti-RPL26 Rabbit Polyclonal Antibody (RPL26/uL24) for WB, IF/ICC, ELISA - P61254

Core Product Specifications and Parameters

Biological Background: RPL26/uL24 Function and Localization

• RPL26, also known as 60S ribosomal protein L26 or uL24, is a component of the large (60S) ribosomal subunit, playing a critical role in protein synthesis. Related references: PMID:23636399 PMID:26100019 PMID:32669547
• Mutations in the RPL26 gene are associated with Diamond-Blackfan anemia, a congenital bone marrow failure syndrome.
• The protein is predominantly localized in the cytoplasm, where ribosomes are abundant.
• Post-translational modifications include phosphorylation, isopeptide bond formation, and ubiquitination, which may regulate ribosome function.
• The theoretical molecular weight of RPL26 is approximately 17.3 kDa.

Experimental Guidance and Technical Tips

• The immunogen covers amino acids 20–95, a region highly conserved among human, mouse, and rat, consistent with the observed cross-reactivity.
• For Western blotting, a band of ~17 kDa is expected; validate specificity using appropriate positive and negative controls.
• In immunofluorescence/immunocytochemistry, anticipate cytoplasmic staining; optimize fixation and permeabilization conditions for your cell type.
• For ELISA, consider pairing with a capture antibody if designing a sandwich assay, or use direct detection for antigen quantitation.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your one-stop partner for IVD raw-material sourcing, offering validated antibody pairs, monoclonal and polyclonal antibodies, and bulk ancillary reagents. This anti-RPL26 antibody supports ribosomal protein research, and we can assist with rare target sourcing and custom antibody development needs—connecting diagnostic manufacturers and researchers with the materials required for every stage from concept to clinic.