Anti-RPL19 Polyclonal Antibody for WB, IHC-P, IF/ICC, ELISA - P84098

Core Product Specifications and Parameters

Biological Background: RPL19 Function and Localization

• RPL19 encodes the 60S ribosomal protein L19, a core component of the large ribosomal subunit. Related references: PMID:23636399 PMID:32669547
• As a ribosomal protein, RPL19 is essential for ribosome assembly and protein synthesis, participating in mRNA translation.
• RPL19 contains conserved domains typical of the eukaryotic ribosomal protein L19 family.
• Localizes to the cytoplasm, consistent with its role in ribosomal function.
• Undergoes multiple post-translational modifications, including phosphorylation, citrullination, and ubiquitination (isopeptide bond formation and Ubl conjugation).
• Structural studies (3D-structure keyword) have elucidated its position within the ribosomal subunit, contributing to our understanding of translation mechanisms.

Experimental Guidance and Technical Tips

• For WB, the predicted molecular weight of RPL19 is approximately 23 kDa; ensure appropriate gel percentage and transfer conditions.
• The immunogen is a synthetic peptide from the N-terminal region (aa1-100) of human RPL19; confirm sequence conservation with target species (human, mouse, rat).
• For IHC-P and IF/ICC, consider antigen retrieval methods and antibody dilution optimization based on tissue or cell type.
• ELISA can be used for quantitative detection; validate in the relevant sample system.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your dedicated partner for IVD raw-material sourcing, offering a comprehensive portfolio including validated antibodies like this anti-RPL19 polyclonal antibody for ribosomal and translation studies. With capabilities in bulk reagent supply, custom antibody development, and technical support, we help streamline your diagnostic assay development from concept to clinic.